Research Articles

Personalising transcranial magnetic stimulation for depression using neuroimaging: A systematic review

The anatomical and electrophysiological characteristics of the brain vary between people, therefore there has been much investigation into personally tailoring TMS treatment to an individual’s brain to maximise treatment outcomes. The most common method involves using MRI-assed neuronavigation. This article offers a systematic review of the current literature of personalised TMS treatment, utilising neuronavigation software.

This review includes 37 studies (1451 patients total), 30 studies of which used neuroimaging to personalise treatment. Seven studies utilised EEG to personalise the frequency of treatment, and six studies directly compared standard TMS with personalised, neuronavigated TMS. The paper demonstrates that neuroimaging can successfully help personalise the treatment of depression and other conditions to provide increased benefits.